منابع مشابه
Crystalline Desoxyribonuclease
A study was made of the enzymatic properties of crystalline desoxyribonuclease. The general effect of the crystalline enzyme on its specific substrate, thymus nucleic acid, was found to be essentially the same as described by previous workers for the digestive action of crude preparations of the enzyme. The digestive action consists mainly in splitting thymus nucleic acid into fragments approac...
متن کاملThe intravenous injection of bovine crystalline pancreatic desoxyribonuclease into patients.
In connection with investigations of streptococcal desoxyribonuclease contained in Varidase@,2 comparative observations have included the intravenous administration of crystalline pancreatic desoxyribonuclease in patients (1). Crystalline pancreatic desoxyribonuclease (referred to throughout this article as PD) has been isolated from beef pancreas and its general properties determined (24). The...
متن کاملStudies on desoxyribonuclease in systemic lupus erythematosus; non-participation of serum desoxyribonuclease in the L.E. phenomenon.
In 1948, Hargraves, Richmond, and Morton (1) described a new cellular element in the bone marrow of patients with acute systemic lupus erythematosus. This element, referred to as the "L.E. cell," has been confirmed by a number of investigators, and has been suggested as a diagnostic aid (2). The L.E. cell may be formed during the incubation of normal homologous or heterologous leucocytes (3) wi...
متن کاملSome Aspects of the Desoxyribonuclease Activities of Animal Tissues
It has been found that many animal tissues contain "acid" desoxyribonucleases with pH optima near 5.2. A chemical method for the determination of this activity is described. The pancreatic desoxyribonuclease crystallized by Kunitz and shown to have a neutral pH optimum occurs in the pancreas together with the "acid" enzyme, but only the "neutral" enzyme occurs in the pancreatic juice. The ratio...
متن کاملPurification and Properties of Desoxyribonuclease Isolated from Beef Pancreas* By
The isolation of crystalline ribonuclease by Kunitz (1) provided a specific enzymatic reagent which has been widely used in the study of ribonucleic acid. Our interest in obtaining a purified preparation of the corresponding enzyme acting on nucleic acid of the desoxyribose type arose in connection with studies on the chemical nature of the substance inducing transformation of pneumococcal type...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1950
ISSN: 1540-7748,0022-1295
DOI: 10.1085/jgp.33.4.349